Nefazodone or Serzone is used to treat depression.
Nefazodone or Serzone inhibits the reuptake of neuro chemicals such a serotonin and norepinephrine in the nervous system. With more of these circulating neuro chemicals, the nervous system is able to function better.
Nefazodone or Serzone use is associated with headache, sleepiness, dry mouth, nausea, dizziness, blurred vision, and sometimes a drop in blood pressure when standing or sitting up quickly. Men taking Nefazodone or Serzone may experience problems with their sex life, however the problems are less common than with other anti depressant drugs. With time these side effects may wear off or become tolerable.
Several weeks of therapy are needed to see results with Nefazodone or Serzone.
Nefazodone or Serzone can increase levels of terfenadine and astemizole which may lead to heart beat irregularities. Because Nefazodone or Serzone can delay the metabolism of triazolam and alprazolam, lower doses of these drugs may be required.
Nefazodone or Serzone should not be combined with another class of anti depressant drugs known as monoamine oxidaseinhibitors - MAOI. If a person is to be changed from one to the other there needs to be a "wash out" period - 14 days when stopping a MAOI; 7 days when stopping Nefazodone or Serzone.
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The relevant product monographs must be regarded as the appropriate sources of prescribing information.