Mirtazepine or Remeron is an antidepressant.
Mirtazepine or Remeron is an alpha 2 antagonist. It blocks receptors to increase the release of norepinephrine and serotonin. It also blocks specific serotonin receptors. The result is the increase of these two neuro chemicals in the nervous system.
Mirtazepine or Remeron has fewer side effects than usually seen with antidepressant drugs - less anxiety, insomnia, nausea. In fact it is able to alleviate some of the anxiety.
The side effects most often seen are drowsiness, increased appetite, and weight gain.
Mirtazepine or Remeron requires several weeks to have its maximum effects, thus people have to be patient to see if it is effective.
Because Mirtazepine or Remeron causes drowsiness, it will interact with any other drug - including alcohol - which may produce drowsiness.
J Clin Psychiatry 1995;56:519
The relevant product monographs must be regarded as the appropriate sources of prescribing information.