The quinupristin and dalfopristin combination is a synergistic antibiotic which uses streptogramins.
It is used in resistant infections - vancomycin resistant enterococci, methicillin resistant staphloccocus, penicillin resistant pneumococcus.
The combination antibiotic inhibits bacterial protein synthesis effectively eradicating the infection.
The most frequent side effects of the combination are local irritation, muscle aches, and generalized malaise.
Because the combination antibiotic can produce elevated liver enzymes, people with liver disease should use these streptogramin antibiotics under medical supervision.
The combination antibiotic is often used in combination with other antibacterial agents.
FDC Reports 1996;58(2):T&G-12
Diag Microbiol Infect Dis 1995;21:169
The relevant product monographs must be regarded as the appropriate sources of prescribing information.