Levofloxacin (Levaquin) Antibiotic Drug: Use, Side Effects, Interactions

Levofloxacin
(Levaquin, United States and Canada)

Use:

Levofloxacin or Levaquin is a quinolone antibiotic used to treat pneumonia and bronchitis.

How It Works:

Levofloxacin or Levaquin interferes with bacterial DNA, and thus bacterial ability to reproduce. It is active against gram positive bacteria including penicillin resistant Strep pneumoniae.

Side Effects:

Levofloxacin or Levaquin is generally well tolerated, however skin rashes, nausea, and diarrhea have been reported.

Cautions for People:

Levofloxacin or Levaquin is a quinolone antibiotic and these antibiotics seem to be involved in joint problems, specifically tendinitis, thus people at increased risk for this type of problem should be closely monitored.
Pregnant women and lactating mothers should use Levofloxacin or Levaquin with care.

Drug Interactions:

Given with theophylline, Levofloxacin or Levaquin can increase theophylline blood levels. It can also increase the effects of the anticoagulant warfarin.
Antacids or highly buffered drugs can reduce Levofloxacin or Levaquin's absorption. In fact taking Levofloxacin or Levaquin with an acidic beverage such as a cola drink may increase its absorption.

Further Reading:

Medical Letter 1997;39:41

Added to Virtual Drugstore December 1997.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.