Pantoprazole (Pantoloc) Drug for Ulcer Disease: Use, Side Effects, Interactions

Pantoprazole
(Pantoloc, United States and Canada)

Use:

Pantoprazole or Pantoloc is used to treat ulcer disease and reflux conditions.

How It Works:

Pantoprazole or Pantoloc inhibits proton pumps in the stomach which produce acid. Thus it reduces acid and provide control of ulcer disease and reflux conditions.
Reflux occurs when the acidic stomach contents reflux or move back up the esophagus to produce a burning sensation or heartburn.

Side Effects:

Pantoprazole or Pantoloc is well tolerated with most side effects being mild and transient. Reported side effects include diarrhea, gas, constipation, abdominal pain, headache, and dizziness, but all less than 1%.

Cautions for People:

Pantoprazole or Pantoloc seems to have a greater effect in the elderly, thus the dosage may have to be modified. Because the liver is involved in the metabolism and excretion of Pantoprazole or Pantoloc, people with liver disease may have to have a dosage modification.

Drug Interactions:

Pantoprazole or Pantoloc is used with various antibiotic combination to treat H. pylori infections which are implicated in ulcer disease.

Further Reading:

Drugs 1996;51:460
Clin Pharmacolkinet 1996;31:9

Added to Virtual Drugstore December 1997.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.