Lansoporazole or Prevacid is used to reduce acid in the stomach especially in conditions like ulcers.
Lansoporazole or Prevacid inhibits something known as proton pumps which are responsible for the production of acid in the stomach. As well, Lansoporazole or Prevacid may have some anti bacterial action against Helicobacter pylori, the organism thought to be involved in ulcer formation.
Lansoporazole or Prevacid's acid suppressing action begins one to two hours after the first dose which is slightly faster than omeprazole. After stopping Lansoporazole or Prevacid, acid secretion returns to normal in two to four days.
Lansoporazole or Prevacid is generally well tolerated. Abdominal pain, nausea, and diarrhea have been reported.
People may be concerned about Lansoporazole or Prevacid's, and even omeprazole's, link to gastric tumours. Lansoporazole or Prevacid given to rats in high doses for over two years, showed some evidence of these tumours. However, the doses were much higher than average doses in people. It is thought that these tumours are related to prolonged suppression of acid.
Lansoporazole or Prevacid's absorption is delayed by sucralfate, and theophylline levels may be effected by Lansoporazole or Prevacid.
Med Letter 1995;37:63
J Clin Gastroenterol 1995:20Suppl:S7
The relevant product monographs must be regarded as the appropriate sources of prescribing information.