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Etodolac (Ultradol, Lodine) Drug for Pain: Use, Side Effects, Interactions




Etodolac
(Ultradol, Canada; Lodine, United States)

More drugs used for Pain.

Use:

Etodolac, Ultradol or Lodine is used to reduce inflammation and pain.

How It Works:

Etodolac, Ultradol or Lodine is a non steroidal anti inflammatory drug which inhibits prostaglandin synthesis at sites of inflammation. Without prostaglandins, inflammation is reduced.

Side Effects:

Etodolac, Ultradol or Lodine like all non steroidal anti inflammatory drugs is able to cause gastro intestinal irritation. However, these problems appear to be less with Etodolac, Ultradol or Lodine than with other non steroidal anti inflammatory drugs.

Cautions for People:

Because Etodolac, Ultradol or Lodine causes stomach irritation, people with sensitive stomachs or a history of ulcer disease should not use it. A cross sensitivity among non steroidal anti inflammatory drugs exists, thus people who are sensitive or even allergic to one member of this groups of drugs will have the same problems with Etodolac, Ultradol or Lodine. Long term use of Etodolac, Ultradol or Lodine can lead to kidney damage and people with existing kidney problem should use Etodolac, Ultradol or Lodine with care.

Drug Interactions:

Etodolac, Ultradol or Lodine is able to reduce protein binding of the blood thinner, warfarin. Because Etodolac, Ultradol or Lodine can affect the functioning of both the liver and kidney, it can alter levels of various drugs in the body - digoxin, beta blockers like propranolol, lithium, methotrexate. A dosage adjustment may be required.

Further Reading:

Drugs 1991;42:274
Med Letter 1991;33:79
Am J Gastroenterol 1993;88:1318
Am Fam Phys 1994;49:1197

Added to Virtual Drugstore August 1996.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.













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