Valsartan (Diovan) Drug for High Blood Pressure: Use, Side Effects, Interactions

Valsartan
(Diovan, United States and Canada)

Use:

Valsartan or Diovan is used for blood pressure control.

How It Works:

In the body the angiotensin-renin system is involved in blood pressure control. Valsartan or Diovan blocks one part of this system - angiotensin II - at its receptor sites. Angiotensin II, thus, is unable to act - blood vessel constriction and salt and water retention does not occur.

Side Effects:

Allergy, stomach irritation, dizziness, too low a blood pressure, and alterations in taste have been reported, however their occurrence is not common. One side effect that is problematic with other types of drugs that affect the angiotensin-renin system is a cough. Valsartan or Diovan does not seem to be associated with a cough.

Cautions for People:

Because Valsartan or Diovan affects the angiotensin-renin system and this system is intimately linked to kidney function, people with kidney problems should be evaluated thoroughly before they take Valsartan or Diovan.

Drug Interactions:

Valsartan or Diovan is commonly used in combination with other cardiovascular drug. Care must be taken if a potassium supplement is given along with Valsartan or Diovan - too high potassium levels may occur.

Further Reading:

Clin Pharmacol Ther 1996;60:341
Clin Pharmacol Ther 1996;61:35
Medical Letter 1997;39:43

Added to Virtual Drugstore December 1997.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.