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Anastrozole (Arimidex) Drug for Cancer: Use, Side Effects, Interactions




Anastrozole
(Arimidex, United States and Canada)

More drugs used for Cancer.

Use:

Anastrozole or Arimidex is used in treating advanced breast cancer. It is reserved for post menopausal women whose cancer has progressed in spite of treatment with drugs like tamoxifen.

How It Works:

Anastrozole or Arimidex taken orally inhibits the enzyme aromatase. By blocking this enzyme, the production in the body's tissues of estrogen is also blocked. It is thought that some forms of breast cancer are stimulated by estrogen, and by reducing amounts of estrogen in the body the progression of the disease is halted.

Side Effects:

Anastrozole or Arimidex's side effects are similar to megestrol's, with one exception - there is less weight gain. The side effects include enlarged breasts, phlebitis of veins, hair loss, blood clots in the lungs, and carpal tunnel syndrome.

Cautions for People:

People with blood clotting or circulation problems must be monitored closely. Because Anastrozole or Arimidex interferes with female hormones, women who are or may be pregnant should avoid the drug.

Drug Interactions:

Anastrozole or Arimidex is able to enhance the effects of drugs that affect blood clotting and circulation.

Further Reading:

J Steroid Biochem Moler Bio 1995;53:175
J Steroid Biochem Moler Bio 1994;49:281

Added to Virtual Drugstore August 1996.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.













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