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Levalbuterol (Xopenex) Drug for Bronchospasm: Use, Side Effects, Interactions




Levalbuterol
(Xopenex, United States)

More drugs used for Bronchospasm.

Use:

Levalbuterol or Xopenex is the R isomer of salbutamol and is used for the prevention and treatment of bronchospasm. Salbutamol (albuterol) is a mixture of two isomers - R and S. It is thought that the R isomer is the more active compound and that the S isomer contributes to some of salbutamol's side effects.

How It Works:

Levalbuterol or Xopenex is a beta 2 adrenergic agonist which targets beta 2 sites in the bronchial tissue to produce relaxation of the bronchial tubes opening air ways.

Side Effects:

Nervousness and tremor are the most commonly reported side effects. Others reported include headache, leg cramps, anxiety, dizziness, chest pain, and heart palpitations.

Cautions for People:

Levalbuterol or Xopenex is available only for use with a nebulizer, and thus people must be familiar with the technique for nebulizer use.

Drug Interactions:

Levalbuterol or Xopenex like salbutamol has the potential to reduce potassium levels when given in combination with non potassium sparing diuretics or oral corticosteroids. Beta blockers reduce its effectiveness and it can reduce digoxin's effectiveness.

Further Reading:

Medical Letter 1999;41(1054):51

Added to Virtual Drugstore September 1999.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.













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