Generic Name : MITOMYCIN
Pronunciation : (mye toe mye' sin)
Trade Name(s) : Mitodus, Mitomycin - C, Mitonco
Why it is prescribed: Mitomycin belongs to the group of
medicines known as antineoplastics. Mitomycin is chemotherapy
that is given as a treatment for some types of cancer. Mitomycin
interferes with the growth of cancer cells, which are eventually
destroyed. Since the growth of normal body cells may also be affected
by mitomycin, other effects will also occur.
When it is to be taken: Mitomycin is to be administered
only by or under the immediate supervision of your doctor. It
is available as Parenteral Injection.
How it should be taken: The dose of mitomycin will be different
for different patients. The dose that is used may depend on a
number of things, including what the medicine is being used for,
the patient's size, and whether or not other medicines are also
being taken. If you are receiving mitomycin at home, follow your
doctor's orders or the directions on the label . If you have any
questions about the proper dose of mitomycin, ask your doctor.
Special Instruction :
1. Tell your doctor if you have ever had any unusual or allergic
reaction to mitomycin.
2. Tell your doctor if you are pregnant or if you intend to have
children. There is a chance that this medicine may cause birth
defects if either the male or female is taking it at the time
of conception or if it is taken during pregnancy. Studies have
shown that mitomycin causes birth defects in animals. In addition,
many cancer medicines may cause sterility which could be permanent.
Although sterility has not been reported with this medicine, the
possibility should be kept in mind.
3. Be sure that you have discussed this with your doctor before
taking this medicine. It is best to use some kind of birth control
while you are receiving mitomycin. Tell your doctor right away
if you think you have become pregnant while receiving mitomycin.
4. Tell your doctor if you are breast-feeding or if you intend
to breast-feed during treatment with this medicine. Because mitomycin
may cause serious side effects, breast-feeding is generally not
recommended while you are receiving it.
Side Effects :
1. Black, tarry stools; blood in urine or stools; cough or hoarseness;
fever or chills; lower back or side pain; painful or difficult
urination; pinpoint red spots on skin; unusual bleeding or bruising
are less common.
2. Redness or pain, especially at place of injection can occur.
3. Cough; decreased urination; shortness of breath; sores in mouth
and on lips; swelling of feet or lower legs.
4. Mitomycin can temporarily lower the number of white blood cells
in your blood, increasing the chance of getting an infection.
It can also lower the number of platelets, which are necessary
for proper blood clotting. If this occurs, there are certain precautions
you can take, especially when your blood count is low, to reduce
the risk of infection or bleeding.
Other Precautions :
1. Although there is no specific information comparing use of
mitomycin in children with use in other age groups, it is not
expected to cause different side effects or problems in children
than it does in adults.
2. Many medicines have not been studied specifically in older
people. Therefore, it may not be known whether they work exactly
the same way they do in younger adults or if they cause different
side effects or problems in older people. There is no specific
information comparing use of mitomycin in the elderly with use
in other age groups.
3. The presence of other medical problems may affect the use of
mitomycin. Make sure you tell your doctor if you have any other
medical problems, especially: Bleeding problems, Chickenpox or
Herpes zoster.
Storage Conditions : Keep the drug away from children,
as it is very harmful.