This article is from the Sacramento FAQ, by David F. Prenatt, Jr. with numerous contributions by others.
Sacramento is located at the Intersection of Interstate 5 (I-5) and
Interstate 80 (I-80), approximately 100 miles northeast of San
Francisco. If you are coming to Sacramento from Southern or Central
California, take I-5 North (or alternatively Route 99 North, if it is
closer); from the San Franciso Bay Area, take I-80 East; from Northern
California, take I-5 South (or Route 70/99 South if it/they are
closer); from Nevada take I-80 West or the legendary coast-to-coast
Route 50 West (whichever is closer). The Sacramento International
Airport is located on the remote northwest edge of Sacramento County
and is served by ten major airlines.