This article is from the WINE WINdows Emulator FAQ, by Dave Gardner firstname.lastname@example.org with numerous contributions by others.
Wine won't run on any x86 CPU less than an 80386. It is known to also work
in the 80486 and Pentium CPUs. Beyond that, the basic test is, if you can
run X11 now, you should be able to run Wine and MS Windows applications
As always, the faster your CPU, the better. Having a math coprocessor is
unimportant. However, having a graphics accelerated video card supported
by X will help greatly.