Dexfenfluramine (Redux) Drug for Weight Loss: Use, Side Effects, Interactions

Dexfenfluramine
(Redux, United States)

Please note that Dexfenfluramine (Redux) has been recalled from the market.

Use:

Dexfenfluramine or Redux is used as an appetite suppressant.

How It Works:

Dexfenfluramine or Redux is the dextro isomer of fenfluramine - another appetite suppressant. It increase a neuro chemical - serotonin - in the body's nervous system. With increased serotonin levels appetite and carbohydrate cravings are reduced. For people 20% to 30% overweight, Dexfenfluramine or Redux shows results within the first four weeks.
Unlike amphetamines, Dexfenfluramine or Redux is not addictive and can be used long term.

Side Effects:

Dexfenfluramine or Redux's side effects include drowsiness and dry mouth.

Cautions for People:

People taking Dexfenfluramine or Redux should watch for pulmonary hypertension which is a serious lung problem. Symptoms of this condition include poor exercise tolerance, difficulty breathing, water retention, and chest pain.

Drug Interactions:

Dexfenfluramine or Redux cannot be taken with drugs which affect serotonin levels, for example fluoxetine. It can also interact with the mono amine oxidase inhibitor anti depressants.

Further Reading:

Lancet 1992;339:436
Eur J Clin Pharmacol 1995;48:81
Int J Obes 1995;19:181
Am J Clin Nutr 1994;60:647
Int J Obes 1992;16:397
Drugs 1992;43:713,800
Lancet 1991;337:1315

Added to Virtual Drugstore August 1996.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.