Cyclosporin (Sanimmune Neoral) Drug for Transplant Rejection: Use, Side Effects, Interactions

Cyclosporin
(Sanimmune Neoral, United States and Canada)

Use:

Cyclosporin or Sanimmune Neoral is used in cases where there may be immune system problems, for example to prevent transplant rejection. Cyclosporin or Sanimmune Neoral is also used in auto immune conditions, for example psoriasis, rheumatoid arthritis.
Neoral is a microemulsion formulation with more complete and consistent absorption.

How It Works:

Cyclosporin or Sanimmune Neoral interferes with the body's immune response basically preventing the body's immune response.

Side Effects:

Cyclosporin or Sanimmune Neoral can cause kidney problems, increased blood pressure, and tremors. These may be of a serious nature and any one taking Cyclosporin or Sanimmune Neoral is closely followed.

Cautions for People:

Because Cyclosporin or Sanimmune Neoral can cause kidney, blood pressure, and tremor problems, people with any other these pre existing problems must be carefully monitored.

Drug Interactions:

Cyclosporin or Sanimmune Neoral concentrations can be increased by grapefruit juice, oral contraceptives, and calcium channel blockers. Phenytoin can decrease Cyclosporin or Sanimmune Neoral concentrations.

Further Reading:

Med Letter 37(955):73,1995
Drugs 1995;50(5):924

Added to Virtual Drugstore November 1996.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.