Bupropion (Zyban) Drug for Smoking Cessation: Use, Side Effects, Interactions
Bupropion
(Zyban, United States and Canada)
More drugs used for Smoking Cessation.
Use:
Bupropion or Zyban is use to reduce withdrawal symptoms experienced in smoking cessation. Bupropion or Zyban is marketed under the name Wellbutrin as an antidepressant.
How It Works:
Bupropion or Zyban acts at the nervous system level to counteract the symptoms of withdrawal - irritability, dizziness. It also seems to reduce the urge to smoke.
Side Effects:
Because Bupropion or Zyban's effect is on the nervous system, its side effects are also related to the nervous system - drowsiness, dizziness. The degree of side effects may vary widely from person to person.
Cautions for People:
People using other drugs that affect the nervous system or that have nervous system conditions should use Bupropion or Zyban with care.
Drug Interactions:
In combination with other drugs that affect the nervous system, Bupropion or Zyban can enhance nervous system effects. For smoking cessation, Bupropion or Zyban can be used with nicotine replacement therapy - this will increase the success rate.
Further Reading:
JAMA 1996;275:1270
Circulation 1992;86:67
Added to Virtual Drugstore December 1997.
The relevant product monographs must be regarded as the appropriate sources of prescribing information.
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