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Estradiol Vaginal Ring (Estring) Drug for Menopause: Use, Side Effects, Interactions




Estradiol vaginal ring
(Estring, United States and Canada)

More drugs used for Menopause.

Use:

The Estradiol Vaginal Ring or Estring is used instead of estrogen creams for symptoms associated with menopause - vaginal dryness, vaginal itchiness, pain during intercourse, pain during urination, urinary urgency. It is intended to be worn in the vagina continually and delivers a low dose of estrogen for about 90 days.

How It Works:

Side Effects:

The Estradiol Vaginal Ring or Estring is generally well tolerated. Headache, abdominal pain, and vaginal pain or irritation have been reported.
If the Estradiol Vaginal Ring or Estring falls out, the ring can be rinsed and re inserted. Constipation is the most common cause of a fall out. Clearing up the constipation will solve this problem.
During sexual intercourse the Estradiol Vaginal Ring or Estring causes no problems, however it may be removed, then re inserted if it is uncomfortable for either partner.

Cautions for People:

People who have estrogen dependent cancer, vaginal bleeding of unknown origin, or are pregnant should not use the Estradiol Vaginal Ring or Estring.
People undergoing a barium xray should remove the Estradiol Vaginal Ring or Estring first. Because the released estrogen may have an effect on the liver, people with liver disease should have their liver function monitored closely.

Drug Interactions:

Because the Estradiol Vaginal Ring or Estring releases small amounts of estrogen locally, it has little potential to interact with other drugs.
With the low doses being released only locally in the vagina, the lining of the uterus or endometrium does not proliferate. Consequently, progesterone is not needed to prevent this problem.

Further Reading:

Drugs 1990;39:203

Added to Virtual Drugstore August 1996.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.













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