Cefpodoxime, Orelox or Vantin is a cephalosporin antibiotic used in bacterial infections that are susceptible - upper and lower respiratory tract, skin, and urinary tract infections. It is a pro drug, meaning that in the body it is converted into the active antibiotic. It has a broad spectrum of activity, and is available only for injection.
Cephalosporin antibiotics are classified in "generation" according to their antibacterial activity: first generation - cefadroxil, cefazolin, cephalexin, cephalothin, cephapirin, cephradine; second generation - cefaclor, cefamandole, cefmetazole, cefonicid, ceforanide, cefotetan, cefoxitin, cefprozil, cefuroxime, loracarbef; third generation - cefixime, cefoperazone, cefotaxime, Cefpodoxime, Orelox or Vantin, ceftazidime, ceftizoxime, ceftriaxone.
Cefpodoxime, Orelox or Vantin inhibits bacterial cell wall formation and the bacteria dies.
Cefpodoxime, Orelox or Vantin can cause diarrhea, nausea, vomiting, constipation, headache, and fever.
Because there is a cross sensitivity with penicillins, people who are allergic to penicillin should use Cefpodoxime, Orelox or Vantin, and all cephalosporins, carefully.
Cefpodoxime, Orelox or Vantin is excreted through the kidney, thus people need good kidney function.
As with all antibiotics and in combination with other antibiotics, cefepime has the ability to cause bacterial resistance to antibiotics.
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The relevant product monographs must be regarded as the appropriate sources of prescribing information.