Tolterodine (Detrol) Drug for Incontinence: Use, Side Effects, Interactions

Tolterodine
(Detrol, United States)

Use:

Tolterodine or Detrol is indicated for urinary frequency, urgency, and urge incontinence.

How It Works:

Tolterodine or Detrol is an antimuscarinic or anticholinergic drug which is able to inhibit bladder contractions and delay the urge to void. It is similar in action to oxybutynin.

Side Effects:

Tolterodine or Detrol is associated with anticholinergic side effects - dry mouth, drowsiness, decreased sweating, blurred vision, heart beat irregularities, nausea, vomiting, impotence. However, when compared to other anticholinergic drugs used for incontinence, these side effects are less marked, because Tolterodine or Detrol is more specific for the bladder.

Cautions for People:

People who are bothered by the anticholinergic side effects associated with incontinence drugs such as oxybutynin may try Tolterodine or Detrol.
Elderly people and people with heart problems should use all anticholinergic drugs, Tolterodine or Detrol, with care.

Drug Interactions:

Tolterodine or Detrol's anticholinergic side effects may interfere with other drug's effectiveness.

Further Reading:

World J Urol 1997;15:144
Eur J Pharmacol 1997;327:2

Added to Virtual Drugstore May 1998.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.