Dorzolamide and Timolol (Cosopt) Drug for Glaucoma: Use, Side Effects, Interactions

Dorzolamide and timolol
(Cosopt, United States)

Use:

Dorzolamide and timolol are combined in one eye drop and are indicated for controlling intra ocular pressure in such conditions like glaucoma.

How It Works:

Dorzolamide is a carbonic anhydrase inhibitor which reduces the production of the fluid - aqueous humour - found in the eye ball. The build up of this fluid increases the pressure in the eye ball and leads to glaucoma. Timolol is a beta blocker which improves drainage of aqueous humour from the eye ball.

Side Effects:

This combination is associated with side effects of the individual agents. Eye irritation - burning, conjunctivitis, inflammation, itching is the most reported. These effects may diminish with time. Dorzolamide may produce a bitter taste.

Cautions for People:

Timolol can worsen asthma and heart failure, and people with these conditions should avoid the product.

Drug Interactions:

Further Reading:

Drugs Future 1996;21:413

Added to Virtual Drugstore May 1998.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.