Brimonidine (Alphagan) Drug for Glaucoma: Use, Side Effects, Interactions

Brimonidine
(Alphagan, United States and Canada)

Use:

Brimonidine or Alphagan is an eye drop used in glaucoma.

How It Works:

Brimonidone lowers ocular pressure by reducing fluid production in the eye and increasing drainage of fluid from the eye. It is classified as an alpha 2 agonist.

Side Effects:

Brimonidone's most common local side effect is irritation of the eye and most common systemic effects are dry mouth, drowsiness, and dizziness; however it is usually well tolerated.

Cautions for People:

With time brimonidone's effectiveness can diminish, thus people should have their pressure monitored routinely to ensure that the drop is still effective.

Drug Interactions:

Brimonidone is usually used in combination with other eye drops to lower eye ball pressure.

Further Reading:

Arch Ophthalmol 1996;113:77
Mayo Clin Proc 1996;71:689

Added to Virtual Drugstore January 1998.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.