Brimonidine or Alphagan is an eye drop used in glaucoma.
Brimonidone lowers ocular pressure by reducing fluid production in the eye and increasing drainage of fluid from the eye. It is classified as an alpha 2 agonist.
Brimonidone's most common local side effect is irritation of the eye and most common systemic effects are dry mouth, drowsiness, and dizziness; however it is usually well tolerated.
With time brimonidone's effectiveness can diminish, thus people should have their pressure monitored routinely to ensure that the drop is still effective.
Brimonidone is usually used in combination with other eye drops to lower eye ball pressure.
Arch Ophthalmol 1996;113:77
Mayo Clin Proc 1996;71:689
The relevant product monographs must be regarded as the appropriate sources of prescribing information.