Tiagabine or Gabitril is used in epilepsy to control seizures.
Tiagabine or Gabitril inhibits the reuptake of gamma aminobutyric acid (GABA), a neurochemical involved in the functioning of the nervous system. This leaves more GABA in the nervous system and reduces seizures.
Tiagabine or Gabitril is associated with dizziness, headache, drowsiness, tremor, nervousness, and depression. With high doses or even rapid increases in doses, confusion, abnormal thinking, and even difficulty concentrating have been reported.
Tiagabine or Gabitril is intended to be used in people over 12 years of age - studies are otherwise incomplete - and for the treatment of partial seizures. It is intended as an adjunct to other drugs.
Medical Letter 1998;40:45
The relevant product monographs must be regarded as the appropriate sources of prescribing information.