Tiagabine (Gabitril) Drug for Epilepsy: Use, Side Effects, Interactions

Tiagabine
(Gabitril, United States)

Use:

Tiagabine or Gabitril is used in epilepsy to control seizures.

How It Works:

Tiagabine or Gabitril inhibits the reuptake of gamma aminobutyric acid (GABA), a neurochemical involved in the functioning of the nervous system. This leaves more GABA in the nervous system and reduces seizures.

Side Effects:

Tiagabine or Gabitril is associated with dizziness, headache, drowsiness, tremor, nervousness, and depression. With high doses or even rapid increases in doses, confusion, abnormal thinking, and even difficulty concentrating have been reported.

Cautions for People:

Tiagabine or Gabitril is intended to be used in people over 12 years of age - studies are otherwise incomplete - and for the treatment of partial seizures. It is intended as an adjunct to other drugs.

Drug Interactions:

Further Reading:

Medical Letter 1998;40:45

Added to Virtual Drugstore July 1998.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.