Irinotecan or Camptosar is used in the treatment of colorectal cancer.
Irinotecan or Camptosar is a camptothecins or topoisomerase I inhibitor. By blocking this enzyme in cells, damage occurs when the cell replicate, and thus the cancer cell growth is controlled. It is available as an injection.
Irinotecan or Camptosar is second line therapy for cancer that progresses in spite of standard treatment such as 5-fluorouracil.
Irinotecan or Camptosar can cause severe diarrhea, but high doses of loperamide will usually control. Hospitalization may be needed if the diarrhea is severe.
People must realize that while Irinotecan or Camptosar offers an alternative which may optimize therapy, the colon cancer may not be "cured".
Often given in combination with other drugs, Irinotecan or Camptosar affords no untoward drug interactions.
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The relevant product monographs must be regarded as the appropriate sources of prescribing information.