4.1 What injectable medications are available?
Description
This article is from the Impotence FAQ, by Sine Nomine llama@drizzle.com with numerous contributions by others.
4.1 What injectable medications are available?
Three injectable drugs are used, alone or in combination, to treat
Erectile Dysfunction: Prostaglandin E1 (PGE1 -- generic name of
injectable is Alprostadil; brand names are Caverject, Edex),
Phentolamine, and Papaverine. The only drug approved by the US Food
and Drug Administration for injection treatment of Erectile
Dysfunction is alprostadil, although phentolamine and papaverine are
approved as vasodilators for treatment of cardiac arrhythmia and
vascular disorders. These drugs are injected directly into the corpora
cavernosa, where they cause the smooth-muscle relaxation and
blood-vessel dilation that are necessary for an erection. A new
preparation, Invicorp, is in the process of gaining approval in the UK
and Europe. Invicorp combines vasoactive intestinal polypeptide (VIP)
(a vasodilator) with phentolamine.
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