This article is from the Epilepsy FAQ, by Andrew Patrick (email@example.com) with numerous contributions by others.
Excessive sleep deprivation can lower seizure thresholds and possibly
result in a seizure. Lack of sleep is known to be an important
precipitating factor in causing seizures. Other factors that can lower
seizure thresholds are high fever, increased excitement, and changes in
body chemistry. It is important for people with Epilepsy to learn what
kinds of events can trigger seizures for them.