Generic Name : WARFARIN
Pronunciation : (war' far in)
Trade Name(s) : Uniwartin, Warf
Why it is prescribed: Warfarin, an anticoagulant, prevents
harmful blood clots from forming or getting larger.
When it is to be taken: Warfarin is taken as a single dose
every 24 hours. Follow the instructions on your prescription label
carefully, and ask your doctor to explain any part that you do
not understand. To avoid missing a dose, take this medication
at the same time that you do something else every day such as
eating dinner. Record each dose on a calender when you take it.
Do not stop taking this medication unless your doctor tells you
to do so.
How it should be taken: Warfarin comes in the form of tablets.
Your prescription label tells you how much to take at each dose.
Special Instruction :
1. Keep all appointments with your doctor and the laboratory.
Periodic laboratory tests, especially prothrombin time, must be
done to check your response to this drug so that your dose can
be adjusted if necessary. Prothrombin time (PT) tests are repeated
frequently when warfarin therapy is started. Once the correct
dosage is established and you take your medication properly, the
tests can be done less often. Failure to keep appointments for
these tests could resulst in the improper control of bleeding.
2. Avoid any activities that have a high injury risk.
3. Special dietary instructions should be followed. Do not increase
or decrease your consumption of foods containing vitamin K, such
as bacon, liver, green leafy vegetables, and cauliflower, without
discussing your diet with your doctor.
4. If you forget to take a dose, take it soon as you remember.
However, if you do not remember until the next day, do not take
two doses. Take only the scheduled dose. Record the date of the
missed dose and tell your doctor at your next visit, since mising
a dose of warfarin may alter yor prothrombin time. If you miss
doses for two or more days, call your doctor promptly.
Side Effects :
1. Bleeding; vomiting; bloody or black, tarry stools; blood in
the urine; red or dark-brown urine; sudden appearance of bruises;
bloody gums; excessive menstrual bleeding; new or unexpected pain
such as headaches, stomach pain, or backaches. Contact your doctor
at the first sign of bleeding. Your dose may need to be adjusted,
or an antidote may be needed if bleeding is severe.
2. Fatigue, fever, chills, sore throat, mouth sores, rash, itching.
Contact your doctor promptly.
Other Precautions :
1. Women who are pregnant or breast-feeding should inform their
doctors. If you become pregnant while taking warfarin, promptly
notify your doctor.
2. Tell your doctor if you are allergic to aspirin or tartrazine.
3. Do not switch to a different brand name warfarin product because
it may diffier in effect. Many drugs increase or decrease the
anticoagulant effect of warfarin, resulting in bleeding or clot
formation.
4. Tell your doctor what presription and nonprescription drugs
you are taking. It is important that all doctors and dentists
taking care of you know that you take warfarin so that they can
avoid prescribing medications that interfere with its effect.
5. Do not stop taking any medications that you are currently taking
unless directed to do so by your doctor.
6. Do not take any nonprescription drugs without consluting your
doctor.
7. If you have an illness that causes vomiting, diarrhoea, or
fever for more than a few days, contact your doctor. These problems
can change the effect of warfarin.
8. Before taking warfarin, tell your doctor your entire medical
history, especially bleeding problems, diabetes, liver or kidney
disease, high blood pressure, arthritis, and thyroid problems.
Also, tell your doctor if you have an infection or have had recent
surgery.
9. Limit your consumption of alcoholic beverages. Ask your doctor
how much, if any, alcohol you may consume.
10. In the event of an accidental overdose of warfarin, contact
your doctor, poison control center, or nearest hospital emergency
department immediately.
11. Do now allow anyone else to take your warfarin.
Storage Conditions :
1. Keep warfarin in the container it came in, tightly closed,
and out of the reach of children.
2. Store it at room temperature and away from light.