Generic Name : NIACIN
Pronunciation : (nye' a sin)
Trade Name(s) : Nicotinic acid, Nicotinamide
Why it is prescribed: Niacin, a vitamin, is used with diet
changes (restriction of cholesterol and fat intake) to reduce
the amount of cholesterol and certain fatty substances in your
blood. Accumulation of cholesterol and fats along the walls of
your arteries decreases blood flow and, therefore, the oxygen
supply to your heart, brain, and other body parts. Lowering your
level of cholesterol and fats may help to prevent heart disease,
angina, strokes, and heart attacks. Niacin also is used to prevent
and treat pellagra i.e., niacin deficiency, a disease caused by
inadequate diet and other medical problems.
When it is to be taken: Niacin usually is taken two to
four times a day, preferably with meals. Follow the instructions
on your prescription label carefully, and ask your doctor to explain
any part that you do not understand.
How it should be taken: Niacin comes in the form of regular
and extended-release tablets, extended-release capsules, elixir
(oral liquid), and injection form. Your prescription label tells
you how much to take at each dose.
Special Instruction :
1. Keep all appointments with your doctor and the laboratory so
that your response to this medication can be evaluated. You probably
will have periodic blood tests.
2. The major risk factors in developing heart attacks and strokes
are high blood levels of cholesterol and fats, obesity, cigarette
smoking, high blood pressure, and diabetes. Follow your doctor's
advice on smoking, diet, exercise, and weight control.
3. If you have high blood pressure or diabetes, take your medication
regularly and follow your doctor's dietary instructions e.g.,
low-sodium or low-salt diet for high blood pressure.
4. If you take niacin to reduce the amount of cholesterol and
fats in your blood, eat a low-cholesterol, low-fat diet: cottage
cheese, fat-free milk, vegetables, poultry, egg whites, and polyunsaturated
oils and margarines, egg yolks, whole milk, cream, butter, shortening,
lard, pastries, cakes, cookies, gravy, peanut butter, chocolate,
olives, potato chips, coconut, coconut and palm oils, and other
fatty and fried foods.
5. Take the missed dose as soon as you remember it and take any
remaining doses for that day at evenly spaced intervals. However,
if you remember a missed dose at the time of your next dose, omit
the missed dose. Do not take a double dose.
Side Effects :
1. Flushing of face and neck. Avoid hot beverages. This effect
usually lasts for 30 to 60 minutes after taking a dose; the frequency
and severity decrease as you continue to take the drug. Contact
your doctor if flushing persists.
2. Itching, stinging or burning of the skin; headaches; blurred
vision; nausea; vomiting; diarrhea; heartburn; bloating; gas;
hunger pains; oily skin. Take niacin on a full stomach or with
antacids. If these effects persist or are severe, contact your
doctor.
3. Dizziness, faintness, fast heartbeat, yellowing of skin or
eyes. Contact your doctor.
Other Precautions :
1. Before you take niacin, tell your doctor if you are pregnant
or breast-feeding or if you are allergic to aspirin or tartrazine.
2. Before you take niacin, tell your doctor if you have diabetes,
heart disease, gallbladder disease, gout, ulcers, allergies, or
a history of jaundice or liver disease.
3. Before you take niacin, tell your doctor what prescription
and nonprescription drugs you are taking especially medication
for high blood pressure or diabetes.
4. If you take insulin or oral diabetes medication, your dose
may need to be changed because niacin may increase the amount
of sugar in your blood and urine. Consult your doctor before changing
your dose.
5. Do not allow anyone else to take this medication.
Storage Conditions :
1. Keep this medication in the container it came in, tightly closed,
and out of the reach of children.
2. Store in at room temperature.