This article is from the X-Men Comic Books FAQ, by Kate the Short (email@example.com) with numerous contributions by others.
Loads of familiar friends and new characters show up in X2. The plot
is relatively simple: Colonel Stryker is using a drug created from his
mutant son's body in order to control mutants (specifically, Nightcrawler
and Deathstrike) as assassins. Stryker also raids the mansion and is able
to capture several students. The X-Men discover this plot and work for a
brief time with Magneto and Mystique (she having broken him out of jail)
in order to rescue their students. They also need to rescue Xavier, who
has also been kidnapped and is being brainwashed into killing all of the
mutants on earth via his Cerebro machine. At the end of the film, Pyro
goes off with Magneto and Mystique, Wolverine leaves Stryker to drown,
and Jean gives her life to allow the X-jet to take off. In the final
scene, Rogue, Bobby, and Kurt all appear in uniform with the X-Men team.
Cameo-wise, there are a few goodies. Colossus armors up and helps the
students escape from the mansion when Stryker attacks. Kitty is seen
phasing through a wall, while Siryn is seen giving off her trademark
scream. Jubilee is among the kidnapped students held at Stryker's base.
Hank McCoy and Sebastian Shaw are seen in a televised talk show debate
that is playing when Mystique seduces Magneto's prison guard in a bar.
A student with a forked tongue by the name of Artie doesn't remotely
match any characteristics of the character found in the comics, and
there doesn't seem to be a match for another young boy who can change
TV channels just by blinking. There are also *many* X-Men and Marvel
characters and organizations listed as file folders when Mystique, as
Deathstrike, breaks into Stryker's computer system to download the
plans of his hidden base.