This article is from the Afghan Hound Breed FAQ, by Janis Nixon with numerous contributions by others.
For a large breed, the Afghan lives a long time. 12 to 14 years is not
unusual, and healthy 18 year old animals have been known. Afghans
suffer from many of the same geriatric complaints that other breeds
get, such as failing eyesight and hearing, and arthritis. Cancer and
heart disease take their toll on the breed as well.