This article is from the Cats and the Outside World FAQ, posted to rec.pets.cats newsgroup. Maintained by Cindy Tittle Moore with numerous contributions by others.
Cars
Cats generally don't like travelling in cars. For short trips, put them in carriers to prevent accidents such as getting in the driver's way, or escaping when the door is opened. Some cats are more calm if kept in a pillowcase or a soft gym-bag type of carrier. For long trips (all day or more), use cat carriers, minimize food intake beforehand, and give water every time you stop. Consider getting harnesses and leashes for when you stop. Most motels allow cats. Sometimes you can use temporary fencing to block off the back of your car to give them a roomier "cage"; you can usually then put litterboxes down instead of keeping them for pit stops. Tranquilizers can be obtained from the vet, but not all cats react well to them, and they may make a trip worse than it would have been otherwise (test the cat's reaction to them beforehand). Many cats will sack out after a few hours on the road.
For long-distance trips, make sure the motels take cats beforehand. Some do not, and are very nasty about it if you try to beg a room. AAA lists motels that accept pets.
You might want to carry along water from your home, especially if you are traveling between states. Ice cubes in the water dish allow your cats to have water without it spilling while you're driving (and helps if its hot, too).
If you're traveling in the summer, make sure the cats get lots of air or air conditioning in the car. carry an umbrella or other shade-making device in case you have a breakdown. Keep alert to where the sun is shining in your car (i.e., is it beating down on the back seat where the cats are?)
Trains
Trains vary widely whether or not animals are allowed on passenger cars. Amtrack does not. British Rail permits cats in a basket or cage placed on the floor, seat or luggage rack. The Swedish railway company allows pets in the smoking section of the car, although pet/non-smoker compartments have been recently introduced.
Planes
Many major airlines allow cats that fit with carrier underseat according to the same dimension limits as for underseat baggage. Most airlines will tell you the cat has to be able to stand up in that carrier but won't enforce this. The pet area is not cargo, it's pressurized but possibly not heated or cooled. Get direct flights since the airplane has little climate control for pets or passengers while on the ground (note: "non-stop" and "direct" flights are *not* the same thing, some "nonstop" flights do indeed land, even tho the passenger may never leave the plane). Airlines aren't permitted to take more than one cat per carrier except for kittens. You must call ahead, usually only one carrier is allowed in the cabin, the rest must go into the pet area. Tips:
* Try not to travel when temperatures are outside the 40-80 degrees F range at either end of the flight or at any stops in between.
* Try to travel at off-peak times to minimize delays.
* Use a sturdy kennel with proper ventilation and room for your cat to stand, turn around, and lie down.
* Try not to tranquilize your cat unless absolutely necessary.
Some airlines are better than others. Delta and United have failed to follow standard procedures to protect animals in inclement weather and as a result many animals have died on their flights. They are being fined $300,000 for this negligence by the U.S. Dept. of Agriculture. American, Continental, Pan Am, and TWA have also been fined. The ASPCA has brought charges in about 50 cases in the past five years. Much of this information can be found in "Pets on Planes: Too Often it's a Rough Ride," _Conde Nast Traveler_ magazine, June 1992.
 
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