Zafirlukast
(Accolate, United States and Canada)

More drugs used for Asthma.

Use:

Zafirlukast or Accolate is used in asthma. It is a leukotriene receptor antagonist (LTRA). Leukotrienes are pro anti inflammatory substances which are released when mast cells are exposed to allergens resulting in broncho constriction, edema, and inflammation.

How It Works:

By blocking these receptors, Zafirlukast or Accolate prevents the release of leukotrienes and thus airway inflammation and broncho constriction is also prevented.

Side Effects:

Cautions for People:

People need to take Zafirlukast or Accolate on an empty stomach to increase its absorption.

Drug Interactions:

Further Reading:

J Allerg Clin Immol 1995;95:388
J Allerg Clin Immol 1996;98:1
Drugs 1994;47:12

Added to Virtual Drugstore November 1996.

The relevant product monographs must be regarded as the appropriate sources of prescribing information.

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