Description
This article is from the Interpretation Of
Lab Test Profiles, by Ed Uthman uthman@neosoft.com with
numerous contributions by others.
14 INORGANIC PHOSPHORUS
Hyperphosphatemia may occur in myeloma, Paget's disease of
bone, osseous metastases, Addison's disease, leukemia,
sarcoidosis, milk-alkali syndrome, vitamin D excess, healing
fractures, renal failure, hypoparathyroidism, diabetic
ketoacidosis, acromegaly, and malignant hyperpyrexia. Drugs
causing serum phosphorous elevation include androgens,
furosemide, growth hormone, hydrochlorthiazide, oral
contraceptives, parathormone, and phosphates.
Hypophosphatemia can be seen in a variety of biochemical
derangements, incl. acute alcohol intoxication, sepsis,
hypokalemia, malabsorption syndromes, hyperinsulinism,
hyperparathyroidism, and as result of drugs, e.g.,
acetazolamide, aluminum-containing antacids, anesthetic agents,
anticonvulsants, and estrogens (incl. oral contraceptives).
Citrates, mannitol, oxalate, tartrate, and phenothiazines may
produce spuriously low phosphorous by interference with the
assay.
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