This article is from the Anime FAQ, by Steve Pearl with numerous contributions by others.
The "c" is a soft-c, pronounced like an "s" (not a "ch"). Also, the "a" is long. Roughly, the two syllables sound like "may-sick," as in "Watching this MAY make you SICK."
(This FAQ entry is Copyright 1994, HardKOR Vision-ary Publications. All rights reserved. All lefts reversed. :-)